Problem/Objective: Smoking is a chronic, relapsing condition and many who try to quit experience numerous quit attempts (Fiore, Bailey, & Cohen, 2000). Treating this chronic condition is a particularly significant health concern in Kentucky which leads the nation in adult smoking prevalence and incidence of tobacco-related deaths. The problem is exacerbated by poor access to health care and high poverty rates in rural communities. Persons living in rural Kentucky comprise 44% of the state's population, many within the Appalachian region of the U.S. These health disparities present significant challenges for treating tobacco dependence. This study explores the feasibility of integrating clinic services and community resources for treating rural tobacco users guided by Wagner's chronic care model (CCM). The CCM has been used as a framework for prevention in primary care practices to address health risk behaviors and other chronic conditions. Methods: This study employs a qualitative method including a series of key informant and focus group interviews with healthcare providers in rural community health centers. Attitudes and perceptions about tobacco treatment and the use of the chronic care model are assessed. Results: Findings from key informant and focus group interviews will be presented. Conclusions: Given the high rates of premature death and disease caused by tobacco use in Kentucky, using a chronic care model for tobacco treatment shows promise in medically underserved populations.