Audience: This presentation will benefit researchers and practitioners. Key Points: The MACC (Minnesota Adolescent Community Cohort) study is a multi-level, population-based, observational cohort study of Minnesota adolescents nested in geo-political units (GPUs). We first divided Minnesota into 129 GPUs (e.g., counties, municipalities, urban neighborhoods) and then selected a stratified random sample of 60 GPUs. We established five age cohorts (ages 12 to 16) with approximately 60 adolescents in each cohort (n = 3636 at baseline) and measured, via telephone surveys, adolescent smoking outcomes every six months. We also measured GPU-level tobacco control exposures at least annually. In this session we will first describe the variability in adolescent smoking prevalence among GPUs at baseline and the GPU characteristics associated with that variability. Next, we will report the effects of a major funding cut in state youth tobacco control using latent curve modeling analyses of smoking data from five months after the funding began through two years following its conclusion. Thirdly, we will compare the strength of local CIA policies and their differential impact on adolescent smoking in cities with varying CIA policies. Learning Objectives: Participants will learn variation in the prevalence of adolescent smoking and GPU characteristics associated with that variation, understand changes in adolescent smoking before and after major funding of youth tobacco control programs, and understand the impact of CIA policies on adolescent smoking. Benefits: These three presentations will illustrate the potential of the MACC study to understand the effects of funding decisions and policies on adolescent smoking.